Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832669 | 1.00 | HPGD (0.40) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL31030927 | 0.90 | HPGD (0.39) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL28660932 | 0.90 | HPGD (0.39) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL29832754 | 0.90 | HPGD (0.39) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725848 | 0.86 | HPGD (0.40) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL20475312 | 0.84 | GRIN1 (0.42) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL28664379 | 0.83 | HPGD (0.37) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL28662889 | 0.83 | HPGD (0.37) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL28662766 | 0.82 | HPGD (0.36) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL29832730 | 0.81 | HPGD (0.36) | HPGDTSHRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549052-B | 4-phenyl-1- (pyridine-4-ylmethyl) pyrrolidine-2-ketone derivative and preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2022-09-02 | — | — | CN | disclosed |
| CN-113549052-A | 4-phenyl-1- (pyridine-4-ylmethyl) pyrrolidine-2-ketone derivative and preparation method and application thereof | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 2021-10-26 | — | — | CN | disclosed |