Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22323981 | 1.00 | TDP1 (0.33) | TDP1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28655571 | 1.00 | TDP1 (0.33) | TDP1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL22323715 | 1.00 | TDP1 (0.33) | TDP1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28653389 | 0.89 | TDP1 (0.41) | TDP1CHRM2CHRM1CHRM3 | |
| SCHEMBL22324176 | 0.89 | TDP1 (0.41) | TDP1CHRM2CHRM1CHRM3 | |
| SCHEMBL22324308 | 0.81 | CHRM2 (0.31) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL22325028 | 0.78 | ALDH1A1 (0.34) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL22324964 | 0.78 | ALDH1A1 (0.34) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL25064838 | 0.77 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL25064817 | 0.77 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113661162-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2021-11-16 | — | — | CN | disclosed |