Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30312708 | 0.95 | PTGS1 (0.39) | PTGS1PTGS2MEN1KMT2AADORA2A | |
| Hydrochloric Acid SCHEMBL28329694 | 0.89 | PTGS1 (0.34) | PTGS1PTGS2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28329691 | 0.88 | PTGS1 (0.34) | PTGS1PTGS2MEN1KMT2AADORA2A | |
| Hydrochloric Acid SCHEMBL28670211 | 0.88 | ADORA2A (0.34) | PTGS1PTGS2ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL28878396 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL28660133 | 0.82 | PTGS1 (0.30) | PTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL30557801 | 0.82 | PTGS1 (0.37) | PTGS1PTGS2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28668206 | 0.80 | PTGS1 (0.39) | PTGS1PTGS2MEN1KMT2AADORA2A | |
| Hydrochloric Acid SCHEMBL6903716 | 0.80 | PTGS1 (0.34) | PTGS1PTGS2MEN1KMT2AADORA2A | |
| SCHEMBL28678581 | 0.80 | PTGS1 (0.37) | PTGS1PTGS2MEN1KMT2AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631591-B | Process for producing catalyst component for olefin polymerization, process for producing catalyst for olefin polymerization, and process for producing olefin polymer | 日本聚丙烯株式会社 | 2023-05-05 | — | — | CN | disclosed |
| CN-110483670-B | Metallocene complex and process for producing olefin polymer | 日本聚丙烯株式会社 | 2021-11-30 | — | — | CN | disclosed |