Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31517107 | 1.00 | OXER1 (0.54) | OXER1HTR2AHTR2CTUBB1NPC1 | |
| SCHEMBL30752391 | 0.87 | OXER1 (0.54) | OXER1NPC1RAB9ANOTUMKMO | |
| SCHEMBL28400587 | 0.82 | TFPI2 (0.48) | OXER1HTR2AHTR2CTUBB1RXFP1 | |
| SCHEMBL31517159 | 0.82 | TFPI2 (0.48) | OXER1HTR2AHTR2CTUBB1RXFP1 | |
| SCHEMBL30885550 | 0.81 | FABP4 (0.43) | HTR2AHTR2CTUBB1NPC1RAB9A | |
| SCHEMBL31517225 | 0.81 | TUBB1 (0.38) | OXER1TUBB1RAB9ANOTUMCYP11B1 | |
| SCHEMBL31517142 | 0.81 | KCNH2 (0.47) | OXER1TUBB1NOTUMCCR9CYP11B1 | |
| SCHEMBL18867950 | 0.81 | TFPI2 (0.47) | HTR2AHTR2CTUBB1NOTUMCYP11B1 | |
| SCHEMBL28701515 | 0.81 | TFPI2 (0.47) | HTR2AHTR2CTUBB1NOTUMCYP11B1 | |
| SCHEMBL28685389 | 0.81 | TUBB1 (0.38) | OXER1TUBB1RAB9ANOTUMCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912529-B | Method for synthesizing indole compounds by catalyzing N-aryl amide compounds and vinylene carbonate with ruthenium | 成都大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113735832-B | Preparation method of 7-succinimidyl indole compound | 温州医科大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-113912529-A | Method for synthesizing indole compound by catalyzing N-aryl amide compound and vinylene carbonate with ruthenium | 成都大学 | 2022-01-11 | — | — | CN | disclosed |
| CN-113735832-A | Preparation method of 7-succinimide indole compound | 温州医科大学 | 2021-12-03 | — | — | CN | disclosed |