Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | FRK | P42685 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672953 | 0.82 | DGAT1 (0.36) | MAPTDGAT1MAPK13MAPK12MAPK11 | |
| SCHEMBL29855368 | 0.77 | MAPT (0.35) | CYP2D6MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL22613097 | 0.77 | MAPT (0.35) | CYP2D6MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL30668712 | 0.76 | MAP4K4 (0.39) | CYP2D6MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL20744175 | 0.76 | MAP4K4 (0.39) | CYP2D6MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL28601695 | 0.72 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL1494550 | 0.70 | DGAT1 (0.39) | CYP2D6MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL352030 | 0.69 | FGFR1 (0.35) | EGFRMAPTDGAT1FLT3 | |
| SCHEMBL30296433 | 0.69 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL29854726 | 0.69 | FGFR1 (0.35) | EGFRMAPTDGAT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727975-A | Substituted pyrrolopyridines as JAK inhibitors | 阿克拉瑞斯治疗股份有限公司 | 2021-11-30 | — | — | CN | disclosed |