SCHEMBL2865609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4335978	0.87	GSK3B (0.47)	CDK4CCND1CDK2CCNA2CCND3
	SCHEMBL2867933	0.86	CDK4 (0.42)	CDK4CCND1CDK2CCNA2CCND3
	SCHEMBL2865497	0.85	EGFR (0.43)	CDK4CCND1CDK2CCNA2CCND3
	SCHEMBL4338572	0.85	STK33 (0.47)	NPC1RAB9ATTKLMNAPOLB
	SCHEMBL4335934	0.85	NPC1 (0.46)	ITKNPC1RAB9ALMNAPOLB
	SCHEMBL2864750	0.83	CDK2 (0.43)	CDK4CCND1CDK2CCNA2CCND3
	SCHEMBL2866649	0.82	USP2 (0.48)	MAPK8AURKBNPC1RAB9ATTK
	SCHEMBL4346877	0.82	SMN1; SMN2 (0.46)	CDK4CCND1CDK2CCNA2CCND3
	SCHEMBL4346834	0.82	SMN1; SMN2 (0.46)	CDK4CCND1CDK2CCNA2CCND3
	SCHEMBL2861482	0.81	CDK4 (0.48)	CDK4CCND1CDK2CCNA2CCND3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.