Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660915 | 0.77 | FGFR3 (0.53) | MAPTCYP17A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28661013 | 0.77 | FGFR3 (0.53) | MAPTCYP17A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4293848 | 0.77 | NPC1 (0.52) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28654308 | 0.76 | MAPT (0.46) | MAPTCYP17A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28929389 | 0.76 | CYP17A1 (0.47) | MAPTCYP17A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28655500 | 0.75 | NTRK1 (0.50) | ABL1MAPTCYP17A1SMN1; SMN2KDM4E | |
| SCHEMBL28668942 | 0.75 | FGFR3 (0.47) | MAPTCYP17A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28668115 | 0.74 | LMNA (0.49) | ABL1MAPTCYP17A1ALDH1A1FYN | |
| SCHEMBL28670642 | 0.74 | FGFR3 (0.49) | MAPTCYP17A1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15344199 | 0.74 | PIK3CD (0.48) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |