Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28680171 | 0.85 | MEN1 (0.41) | MEN1KMT2APKMMAPTALDH1A1 | |
| SCHEMBL4344723 | 0.83 | CHRM2 (0.40) | MEN1KMT2APKMCHRM2CHRM1 | |
| SCHEMBL1233750 | 0.81 | CHRM2 (0.46) | MEN1KMT2APKMCHRM2CHRM1 | |
| SCHEMBL1232867 | 0.81 | CHRM2 (0.42) | MEN1KMT2APKMCHRM2CHRM1 | |
| SCHEMBL1041725 | 0.80 | BCHE (0.44) | MEN1KMT2APKMADORA2AMAPT | |
| SCHEMBL1231854 | 0.80 | BCHE (0.48) | MEN1KMT2APKMCHRM2CHRM1 | |
| SCHEMBL1036949 | 0.78 | BRD4 (0.44) | MEN1KMT2ACHRM2CHRM1DRD2 | |
| SCHEMBL1233074 | 0.78 | STK17B (0.44) | MEN1KMT2ACHRM2CHRM1DRD2 | |
| SCHEMBL6724381 | 0.77 | LDHA (0.50) | MEN1KMT2APKMCHRM2CHRM1 | |
| SCHEMBL1041911 | 0.77 | MEN1 (0.45) | MEN1KMT2APKMMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113660957-A | Compositions, methods, and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2021-11-16 | — | — | CN | disclosed |