SCHEMBL28656164

SCHEMBL28656164

O=C(Nc1ccccn1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.76
NPC1 O15118 8/20 0.76
F2 P00734 1/20 0.74
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
CASP3 P42574 1/20 0.67
SENP8 Q96LD8 1/20 0.67
SENP7 Q9BQF6 1/20 0.67
SENP6 Q9GZR1 1/20 0.67
CHRNB2 P17787 1/20 0.65
CHRNB4 P30926 1/20 0.65
CHRNA3 P32297 1/20 0.65
CHRNA4 P43681 1/20 0.65
GRM5 P41594 1/20 0.64
ATM Q13315 1/20 0.64
MAPK14 Q16539 1/20 0.60
TP53 P04637 1/20 0.58
RECQL P46063 1/20 0.58
PGR P06401 1/20 0.58
PKM P14618 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14859655 0.86 RAB9A (0.78) RAB9ANPC1F2MEN1KMT2A
SCHEMBL29366822 0.85 RAB9A (0.89) RAB9ANPC1F2MEN1KMT2A
SCHEMBL997866 0.85 RAB9A (0.89) RAB9ANPC1F2MEN1KMT2A
SCHEMBL12502132 0.85 F2 (1.00) RAB9ANPC1F2MEN1KMT2A
SCHEMBL16583895 0.84 RAB9A (0.86) RAB9ANPC1F2MEN1KMT2A
SCHEMBL7189774 0.84 RAB9A (0.86) RAB9ANPC1F2MEN1KMT2A
Hydrochloric Acid SCHEMBL27681799 0.84 RAB9A (0.86) RAB9ANPC1F2MEN1KMT2A
SCHEMBL6940180 0.83 RAB9A (1.00) RAB9ANPC1F2MEN1KMT2A
SCHEMBL18347891 0.82 RAB9A (0.71) RAB9ANPC1F2MEN1KMT2A
SCHEMBL28721656 0.82 RAB9A (0.71) RAB9ANPC1F2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113735850-A Synthesis method of 1,2, 4-triazole compound 河南师范大学 2021-12-03 CN disclosed