Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.63 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.54 |
| ▸ | FYN | P06241 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17777306 | 0.80 | ROCK2 (0.52) | MAP3K5ROCK2FYNCHEK1FGFR1 | |
| SCHEMBL1836050 | 0.78 | CCNT1 (0.56) | MAP3K5SMN1; SMN2TP53CHEK1FGFR1 | |
| SCHEMBL10059838 | 0.78 | ROCK2 (0.54) | MAP3K5ROCK2FYNNPC1RAB9A | |
| SCHEMBL1570088 | 0.78 | MAP3K5 (0.45) | MAP3K5ROCK2MAPTKDM4EMEN1 | |
| SCHEMBL5612710 | 0.78 | MAPT (0.59) | FYNNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29684484 | 0.78 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL3786463 | 0.77 | NQO2 (0.73) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL2646435 | 0.77 | CNR1 (0.63) | FYNNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL2684195 | 0.77 | ROCK1 (0.68) | ROCK2 | |
| SCHEMBL17280213 | 0.77 | NQO2 (0.51) | FYNNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |