Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.37 |
| ▸ | PRKACG | P22612 | 2/20 | 0.37 |
| ▸ | PRKACB | P22694 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101377 | 0.83 | CDK4 (0.43) | CCNT1CCNA2CDK2CDK9CAMK2D | |
| SCHEMBL19751957 | 0.81 | GSK3B (0.50) | CCNT1CCNA2CDK2CDK9CNR2 | |
| SCHEMBL28671386 | 0.79 | MEN1 (0.44) | CCNT1CCNA2CDK2CDK9MEN1 | |
| SCHEMBL5911539 | 0.79 | CAMK2D (0.62) | CAMK2DPIM1PRKACAPRKACGPRKACB | |
| SCHEMBL27811481 | 0.76 | CDK2 (0.62) | CCNT1CCNA2CDK2CDK9CAMK2D | |
| SCHEMBL29504831 | 0.75 | CCNE2 (0.63) | CDK2 | |
| SCHEMBL5879232 | 0.75 | CCNE2 (0.63) | CDK2 | |
| SCHEMBL28101209 | 0.75 | GSK3B (0.38) | CCNT1CCNA2CDK2CDK9MEN1 | |
| SCHEMBL8112713 | 0.75 | CDK2 (0.71) | CCNT1CCNA2CDK2CDK9CAMK2D | |
| Hydrochloric Acid SCHEMBL29664072 | 0.74 | CCNE2 (0.61) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218206-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-110526903-B | Bisindolylmaleimide derivative and preparation method and application thereof | 中国海洋大学 | 2021-12-10 | — | — | CN | disclosed |