Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721040 | 0.84 | — | — | |
| SCHEMBL7782689 | 0.80 | MGAM (0.43) | MGAMGAASIMGAM2JAK2 | |
| SCHEMBL14389976 | 0.78 | MGAM (0.44) | DGAT1MGAMGAASIMGAM2 | |
| SCHEMBL14389978 | 0.78 | MGAM (0.44) | DGAT1MGAMGAASIMGAM2 | |
| SCHEMBL28876551 | 0.77 | DGAT1 (0.37) | DGAT1MGAMGAASIMGAM2 | |
| SCHEMBL3036111 | 0.77 | MGAM (0.43) | MGAMGAASIMGAM2JAK2 | |
| SCHEMBL1721997 | 0.77 | MGAM (0.43) | DGAT1MGAMGAASIMGAM2 | |
| SCHEMBL21072260 | 0.77 | MGAM (0.43) | DGAT1MGAMGAASIMGAM2 | |
| SCHEMBL18971858 | 0.77 | MGAM (0.43) | DGAT1MGAMGAASIMGAM2 | |
| SCHEMBL1284525 | 0.77 | MGAM (0.43) | DGAT1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493399-A | Preparation method for converting configuration of key intermediate of cariprazine | 北京万全德众医药生物技术有限公司 | 2021-10-12 | — | — | CN | disclosed |