Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069221 | 0.80 | INPP5A (0.39) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL5071937 | 0.77 | KDM4E (0.36) | TSHRSLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL1195857 | 0.77 | TSHR (0.64) | SLC18A3TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1265907 | 0.77 | TSHR (0.48) | SLC18A3TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8414022 | 0.77 | TSHR (0.48) | SLC18A3TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8674396 | 0.77 | TSHR (0.48) | SLC18A3TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1265905 | 0.77 | TSHR (0.48) | SLC18A3TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8675407 | 0.77 | TSHR (0.48) | SLC18A3TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8411227 | 0.74 | FFAR1 (0.37) | KDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL5066891 | 0.73 | MEN1 (0.40) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113544129-B | Tricyclic compound preparation method and application thereof in medicine field | 上海华汇拓医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-113544129-A | Tricyclic compound preparation method and application thereof in medicine field | 上海华汇拓医药科技有限公司 | 2021-10-22 | — | — | CN | disclosed |