Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.74 |
| ▸ | LOX | P28300 | 14/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19274859 | 0.85 | LOXL2 (1.00) | LOXL2LOXKCNH2AOC3LOXL3 | |
| Hydrochloric Acid SCHEMBL19259885 | 0.84 | LOXL2 (1.00) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL20983546 | 0.82 | LOXL2 (0.72) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL28643824 | 0.82 | LOXL2 (0.76) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL28646848 | 0.80 | LOX (0.51) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL28639391 | 0.79 | LOXL2 (0.65) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL29971550 | 0.79 | LOXL2 (0.65) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL28638863 | 0.77 | LOX (0.72) | LOXL2LOXKCNH2AOC3LOXL3 | |
| Hydrochloric Acid SCHEMBL28651636 | 0.75 | LOXL2 (0.69) | LOXL2LOXKCNH2AOC3LOXL3 | |
| SCHEMBL28644255 | 0.74 | LOXL2 (0.76) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |