Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 6/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20750911 | 0.90 | MAP3K5 (0.41) | MAP3K5ABL1RIPK2 | |
| SCHEMBL28649418 | 0.86 | MAP3K5 (0.53) | MAP3K5TTRGAARIPK2 | |
| SCHEMBL28658681 | 0.85 | TLR2 (0.44) | TSHRMAP3K5ABL1ALDH1A1RIPK2 | |
| SCHEMBL28648138 | 0.83 | MAP3K5 (0.41) | MAP3K5ABL1HSD17B10GAAKDM4C | |
| SCHEMBL28657015 | 0.83 | TSHR (0.45) | TSHRMAP3K5ABL1HSD17B10KDM4C | |
| SCHEMBL30029659 | 0.78 | MAP3K5 (0.42) | MAP3K5HSD17B10GAATDP1RIPK2 | |
| SCHEMBL20672223 | 0.78 | MAP3K5 (0.42) | MAP3K5HSD17B10GAATDP1RIPK2 | |
| SCHEMBL27959304 | 0.77 | MAP3K5 (0.52) | MAP3K5KMOHSD17B10GAATDP1 | |
| SCHEMBL28652012 | 0.77 | KDM4C (0.55) | KDM4CKDM4AKDM2B | |
| SCHEMBL21649346 | 0.77 | MAP3K5 (0.50) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400625-B | Fused bicyclic compound and application thereof in medicine | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |