Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL20530383 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL27604303 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL27786672 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL10426646 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL583707 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL27323433 | 0.87 | ALDH1A1 (0.60) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL28062642 | 0.86 | ALDH1A1 (0.82) | ALDH1A1MAPK1MMP3BCL2L1CA1 | |
| Biphenyl SCHEMBL28237118 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL27548822 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPK1MMP3BCL2L1CRHBP | |
| Biphenyl SCHEMBL6561103 | 0.82 | ALDH1A1 (0.90) | ALDH1A1MAPK1MMP3BCL2L1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-214830030-U | Processing system after production bromination of cyano-group bromobiphenyl | 江苏新瑞药业有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-214693951-U | Bromination reaction system for production of cyanoborobiphenyl | 江苏新瑞药业有限公司 | 2021-11-12 | — | — | CN | disclosed |