Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.54 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.53 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30959784 | 0.91 | HSP90AB1 (0.80) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL230368 | 0.90 | HSP90AB1 (0.82) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL21293881 | 0.88 | HSP90AB1 (0.80) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL18028297 | 0.82 | HSP90AB1 (0.70) | HSP90AB1CYP19A1NPC1RAB9A | |
| SCHEMBL10044915 | 0.81 | HSP90AB1 (0.69) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL15425743 | 0.79 | CYP19A1 (0.67) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL17104470 | 0.79 | CYP19A1 (0.67) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL805203 | 0.78 | HSP90AB1 (0.65) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL29055929 | 0.78 | CYP19A1 (0.65) | HSP90AB1CYP19A1NPC1RAB9AHRH4 | |
| SCHEMBL16463657 | 0.77 | HSP90AB1 (0.63) | HSP90AB1CYP19A1NPC1RAB9AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113521296-A | EGFR aptamer modified miR-375 and PTX loaded RNA nano-drug, preparation method and application | 王其龙 | 2021-10-22 | — | — | CN | claimed |
| CN-113499443-A | miR-375 and PTX loaded four-way joint RNA nano-drug and preparation method and application thereof | 王其龙 | 2021-10-15 | — | — | CN | claimed |
| CN-113521296-A | EGFR aptamer modified miR-375 and PTX loaded RNA nano-drug, preparation method and application | 王其龙 | 2021-10-22 | — | — | CN | disclosed |
| CN-113499443-A | miR-375 and PTX loaded four-way joint RNA nano-drug and preparation method and application thereof | 王其龙 | 2021-10-15 | — | — | CN | disclosed |