Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988363 | 0.89 | POLB (0.49) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL28435882 | 0.89 | POLB (0.49) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL28776847 | 0.89 | POLB (0.49) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL27436674 | 0.77 | MAPK1 (0.43) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1899739 | 0.77 | MAPK1 (0.41) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL12256177 | 0.77 | POLB (0.40) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1900630 | 0.77 | POLB (0.38) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL29053833 | 0.76 | — | — | |
| SCHEMBL10602704 | 0.76 | POLB (0.33) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL23080071 | 0.75 | MAPK1 (0.41) | POLBKDM4ESMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115252807-A | Disaggregated cell-penetrating complexes for nucleic acid delivery | 利兰斯坦福初级大学董事会 | 2022-11-01 | — | — | CN | disclosed |
| CN-109963564-B | Disaggregated cell-penetrating complexes for nucleic acid delivery | 利兰斯坦福初级大学董事会 | 2022-08-12 | — | — | CN | disclosed |
| CN-113573740-A | Mixed lytic cell penetrating complexes for nucleic acid delivery | 利兰斯坦福初级大学董事会 | 2021-10-29 | — | — | CN | disclosed |