Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20347136 | 0.90 | PTPN11 (0.85) | PTPN11 | |
| SCHEMBL18328265 | 0.89 | PTPN11 (1.00) | PTPN11 | |
| SCHEMBL28648881 | 0.88 | PTPN11 (0.82) | PTPN11 | |
| SCHEMBL20347129 | 0.86 | PTPN11 (0.79) | PTPN11 | |
| SCHEMBL18328152 | 0.86 | PTPN11 (0.79) | PTPN11 | |
| SCHEMBL19785449 | 0.85 | PTPN11 (0.77) | PTPN11 | |
| SCHEMBL30141213 | 0.84 | PTPN11 (0.75) | PTPN11 | |
| SCHEMBL28642731 | 0.82 | PTPN11 (0.72) | PTPN11 | |
| SCHEMBL19717762 | 0.82 | PTPN11 (0.72) | PTPN11 | |
| SCHEMBL31657083 | 0.82 | PTPN11 (0.72) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057689-A | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-109415360-B | Compounds and compositions for inhibiting SHP2 activity | 诺华股份有限公司 | 2021-11-02 | — | — | CN | disclosed |