Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13874783 | 0.85 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1OPRL1MBTD1CYP2D6 | |
| SCHEMBL13874528 | 0.83 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1OPRL1MBTD1CYP2D6 | |
| SCHEMBL7581493 | 0.80 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1MBTD1CYP2D6CYP2C19 | |
| SCHEMBL13874479 | 0.79 | L3MBTL3 (0.47) | L3MBTL3L3MBTL1OPRL1ALDH1A1 | |
| SCHEMBL20445361 | 0.75 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1OPRL1MBTD1TP53BP1 | |
| SCHEMBL18843591 | 0.75 | L3MBTL3 (0.45) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL23258084 | 0.72 | OPRL1 (0.42) | L3MBTL3L3MBTL1OPRL1MBTD1CYP2D6 | |
| SCHEMBL24681506 | 0.71 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1KDM4EALDH1A1EBP | |
| SCHEMBL24454832 | 0.71 | KMT2A (0.44) | L3MBTL3L3MBTL1OPRL1KDM4E | |
| SCHEMBL22166558 | 0.71 | L3MBTL3 (0.42) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640965-B | 2-substituted-18 beta-glycyrrhetinic acid derivative and application thereof | 沈阳药科大学 | 2021-11-05 | — | — | CN | disclosed |