Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313083 | 0.91 | TRPA1 (0.57) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL4104509 | 0.91 | TRPA1 (0.57) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL28600217 | 0.91 | TRPA1 (0.57) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL11313087 | 0.91 | TRPA1 (0.57) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL868400 | 0.89 | TRPA1 (0.59) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL13952533 | 0.89 | TRPA1 (0.59) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL868399 | 0.89 | TRPA1 (0.59) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL10899903 | 0.82 | MAPT (0.50) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL17304913 | 0.82 | MAPT (0.50) | PPARGGPR132TRPA1DDAH1GAPDH | |
| SCHEMBL28725974 | 0.80 | PPARG (0.56) | PPARGGPR132TRPA1DDAH1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113573592-A | Oral cavity coating feeling enhancer | 味之素株式会社 | 2021-10-29 | — | — | CN | disclosed |