Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867391 | 0.91 | P2RX3 (0.64) | P2RX3P2RX2 | |
| SCHEMBL2856882 | 0.91 | P2RX3 (0.63) | P2RX3P2RX2 | |
| SCHEMBL2858898 | 0.87 | P2RX3 (0.64) | P2RX3P2RX2 | |
| SCHEMBL2859566 | 0.86 | P2RX3 (0.62) | P2RX3P2RX2 | |
| SCHEMBL2867314 | 0.85 | P2RX3 (0.58) | P2RX3P2RX2 | |
| SCHEMBL2876998 | 0.84 | P2RX3 (0.63) | P2RX3P2RX2 | |
| SCHEMBL2861070 | 0.83 | P2RX3 (0.49) | P2RX3P2RX2 | |
| SCHEMBL2865907 | 0.83 | P2RX3 (0.64) | P2RX3P2RX2 | |
| SCHEMBL2858090 | 0.82 | P2RX3 (0.65) | P2RX3P2RX2 | |
| SCHEMBL2866931 | 0.81 | P2RX3 (0.65) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139334-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-01-06 | — | — | EP | claimed |
| WO-2008130481-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-30 | — | — | WO | claimed |
| EP-2139334-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008130481-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |