Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658424 | 0.86 | KDM5A (0.53) | KDM5AKDM4CKDM5BHDAC1P2RX7 | |
| SCHEMBL28925381 | 0.85 | KDM5A (0.49) | KDM5AKDM4CKDM5BCCNT1PIM1 | |
| SCHEMBL22102122 | 0.83 | KDM5A (0.49) | KDM5AKDM4CKDM5BCCNT1PIM1 | |
| SCHEMBL18525587 | 0.83 | KDM5A (0.49) | KDM5AKDM4CKDM5BCCNT1PIM1 | |
| SCHEMBL18525794 | 0.81 | KDM5A (0.59) | KDM5AKDM4CKDM5BPIM1ROCK1 | |
| SCHEMBL28658094 | 0.81 | KDM5A (0.47) | KDM5AKDM4CKDM5BCCNT1PIM1 | |
| SCHEMBL18525795 | 0.81 | KDM5A (0.53) | KDM5AKDM4CKDM5BPIM1L3MBTL1 | |
| SCHEMBL18526087 | 0.80 | MAPK14 (0.53) | KDM5AKDM4CKDM5BHDAC1CCNT1 | |
| SCHEMBL22102194 | 0.78 | KDM5A (0.49) | KDM5AKDM4CKDM5BCCNT1PIM1 | |
| SCHEMBL18526203 | 0.78 | ROCK2 (0.56) | KDM5AKDM4CKDM5BPIM1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412113-A | Aminooxazine amides | 豪夫迈·罗氏有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-113412113-A | Aminooxazine amides | 豪夫迈·罗氏有限公司 | 2021-09-17 | — | — | CN | disclosed |