Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7870981 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Hydrochloric Acid SCHEMBL10684441 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Hydrochloric Acid SCHEMBL29171399 | 1.00 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| SCHEMBL19347553 | 0.98 | TSHR (0.42) | TSHRHPGDMAPTLMNATHRB | |
| SCHEMBL7592554 | 0.98 | TSHR (0.42) | TSHRHPGDMAPTLMNATHRB | |
| SCHEMBL13727578 | 0.98 | TSHR (0.42) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL23088976 | 0.97 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL28628532 | 0.97 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL29140479 | 0.97 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB | |
| Bromide SCHEMBL29140480 | 0.97 | TSHR (0.41) | TSHRHPGDMAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160493-B | Modified polyacrylamide and supermolecule fracturing fluid for improving viscoelasticity and temperature resistance of fracturing fluid and preparation method of modified polyacrylamide and supermolecule fracturing fluid | 四川川庆井下科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-115160493-A | Modified polyacrylamide for improving viscoelasticity and temperature resistance of fracturing fluid, supramolecular fracturing fluid and preparation method of supramolecular fracturing fluid | 四川川庆井下科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-113667466-B | Supermolecule fracturing fluid based on modified polyacrylamide and preparation method thereof | 四川川庆井下科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113667466-A | Supermolecule fracturing fluid based on modified polyacrylamide and preparation method thereof | 四川川庆井下科技有限公司 | 2021-11-19 | — | — | CN | disclosed |