SCHEMBL28658486

SCHEMBL28658486

COC1C=C(c2ccccc2)C=CC1(Cl)CCl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4680504 0.77 HTT (0.33) HTT
SCHEMBL6197717 0.72 HTT (0.30) HTT
SCHEMBL27787199 0.71 HTT (0.35) HTT
SCHEMBL27765501 0.71 HTT (0.35) HTT
SCHEMBL27572799 0.70 ALDH1A1 (0.34)
SCHEMBL29055453 0.69 HTT (0.36) HTT
SCHEMBL28423241 0.69
SCHEMBL27943716 0.69 NPC1 (0.31)
SCHEMBL7534104 0.68 RIPK2 (0.32)
SCHEMBL27787204 0.68 HTT (0.33) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920132-B Small-molecule non-nucleoside compound serving as immunomodulator 齐鲁师范学院 2023-08-15 CN disclosed
CN-112920132-A Small molecule non-nucleoside compound as immunomodulator 齐鲁师范学院 2021-06-08 CN disclosed