Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987867 | 0.91 | MEN1 (0.78) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL95043 | 0.90 | MEN1 (0.68) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL2832296 | 0.85 | MAPT (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL9119912 | 0.85 | RAB9A (0.71) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL28648926 | 0.85 | HDAC6 (0.70) | RAB9AEPHX2PPARGTSHRPOLB | |
| SCHEMBL5647805 | 0.83 | MEN1 (0.68) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL25872270 | 0.83 | MEN1 (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL13947380 | 0.83 | MEN1 (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL19630500 | 0.83 | MEN1 (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A | |
| SCHEMBL6355362 | 0.83 | POLB (0.72) | MEN1KMT2ACYP2C19CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |