SCHEMBL28658697

SCHEMBL28658697

CCOC(=O)c1ccc2cc(O)c(C)cc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.61
CA1 P00915 5/20 0.61
CA2 P00918 5/20 0.61
CA7 P43166 5/20 0.61
CA9 Q16790 5/20 0.61
CA14 Q9ULX7 5/20 0.61
HSD17B2 P37059 1/20 0.55
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
PTPN11 Q06124 1/20 0.51
BCL2L1 Q07817 1/20 0.50
STS P08842 1/20 0.48
LMNA P02545 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP1A2 P05177 1/20 0.47
MAOA P21397 1/20 0.47
MEN1 O00255 1/20 0.45
TP53 P04637 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979785 0.87 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL707407 0.87 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL1960994 0.85 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL28659587 0.84 LCK (0.58) CA12CA1CA2CA7CA9
SCHEMBL3918302 0.84 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL5750863 0.84 HSD17B2 (0.71) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL3914854 0.82 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL3914848 0.82 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL2128648 0.82 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL2761208 0.82 CA12 (0.57) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748021-A Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2021-12-03 CN disclosed