SCHEMBL2128648

SCHEMBL2128648

CCOC(=O)c1ccc2cc(O)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.68
CA1 P00915 5/20 0.68
CA2 P00918 5/20 0.68
CA7 P43166 5/20 0.68
CA9 Q16790 5/20 0.68
CA14 Q9ULX7 5/20 0.68
ESR1 P03372 2/20 0.68
ESR2 Q92731 1/20 0.68
HSD17B2 P37059 1/20 0.55
LMNA P02545 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
TP53 P04637 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MAOA P21397 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
PTPN11 Q06124 1/20 0.51
MIF P14174 1/20 0.51
PFKFB3 Q16875 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041394 0.95 CA12 (0.66) CA12CA1CA2CA7CA9
SCHEMBL707407 0.91 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL9979785 0.87 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL5599708 0.87 ESR1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL19763407 0.86 ESR1 (0.53) CA12CA1CA2CA7CA9
SCHEMBL1960994 0.85 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL16259100 0.84 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL7642823 0.84 HRH3 (0.61) CA12CA1CA2CA7CA9
SCHEMBL15724963 0.84 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL30684671 0.84 CA12 (0.59) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447534-A 6-[(7-chloroquinoline-4-oxyl) phenolic ether]-2-naphthamide derivative as well as preparation method and application thereof UNIV XIAMEN 2015-03-25 CN claimed
CN-103159943-B Method for synthesizing liquid crystal polyester by using rare earth catalyst KINGFA TECHNOLOGY CO., LTD. (CN) 2014-10-29 CN claimed
CN-103923004-A Naphthalene formamide derivative and preparation and application thereof UNIV HUAQIAO 2014-07-16 CN claimed
CN-103896836-A N-benzyl-6-[(7-chloroquinoline-4-oxo) phenolic ether]-2-naphthamide and preparation method thereof UNIV HUAQIAO 2014-07-02 CN claimed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US claimed
JP-59146894-A None JP disclosed
JP-59146893-A None JP disclosed
CN-118063355-A Preparation method of high-purity adapalene intermediate 6- (p-toluenesulfonyloxy) -2-naphthoate 杭州善礼生物医药科技有限公司 2024-05-24 CN disclosed
CN-113845635-A Polyhydroxy resin, method for producing same, epoxy resin composition containing same, and cured epoxy resin 日铁化学材料株式会社 2021-12-28 CN disclosed
CN-113698292-A Preparation method of 6-hydroxy-2-naphthoic acid 宿迁思睿屹新材料有限公司 2021-11-26 CN disclosed
CN-113698292-A Preparation method of 6-hydroxy-2-naphthoic acid 宿迁思睿屹新材料有限公司 2021-11-26 CN disclosed
US-10844163-B2 Functional spirocyclic polymers and methods of preparation thereof THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2020-11-24 US disclosed
EP-0151299-A2 Aromatic polyester, process for production thereof and film, fiber and other shaped articles therefrom TEIJIN LIMITED (JP) 1985-08-14 EP disclosed
US-4518612-A Naphthalene and 2-oxo-benzopyran acids and derivatives and pharamaceutical use thereof FISONS PLC (GB) 1985-05-21 US disclosed
EP-0123543-A1 Leukotriene antagonists, their production and use and compositions containing them MERCK FROSST CANADA INC. (CA) 1984-10-31 EP disclosed
JP-S59146893-A THERMAL RECORDING MATERIAL RICOH CO LTD 1984-08-22 JP disclosed
JP-S59146894-A THERMAL RECORDING MATERIAL RICOH CO LTD 1984-08-22 JP disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4424231-A Compounds FISONS LIMITED (GB) 1984-01-03 US disclosed
EP-0061800-A1 Anti SRS-A carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them FISONS plc (GB) 1982-10-06 EP disclosed