Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655211 | 1.00 | PARP11 (0.37) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL28499172 | 1.00 | PARP11 (0.37) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL28513382 | 0.94 | PARP1 (0.38) | PARP10PIM1PIM2GPR119PARP1 | |
| SCHEMBL28654294 | 0.86 | S1PR2 (0.38) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL28499175 | 0.86 | S1PR2 (0.38) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL21768121 | 0.85 | PARP10 (0.42) | PARP11PARP10PRKACAPRKACGPRKACB | |
| SCHEMBL28495609 | 0.83 | AOC3 (0.44) | FNTAFNTBGRM5DDB1CRBN | |
| SCHEMBL28492016 | 0.83 | AOC3 (0.44) | FNTAFNTBGRM5DDB1CRBN | |
| SCHEMBL28497819 | 0.80 | AOC3 (0.47) | FNTAFNTBDDB1CRBN | |
| SCHEMBL28497757 | 0.80 | PARP1 (0.34) | PIM1PIM2PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113748104-B | Isoquinolinones for inhibiting SSAO/VAP-1 and application thereof | 广东东阳光药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-113748104-A | Isoquinolinone compound for inhibiting SSAO/VAP-1 and application thereof | 广东东阳光药业有限公司 | 2021-12-03 | — | — | CN | disclosed |