Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.41 |
| ▸ | PAK4 | O96013 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651103 | 0.90 | HDAC3 (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28664143 | 0.88 | SNCA (0.48) | HDAC1EGLN1MEN1KMT2A | |
| SCHEMBL28655462 | 0.85 | GRN (0.38) | ALDH1A1KDM5CKDM4CKDM2AKDM3A | |
| SCHEMBL15055622 | 0.83 | ALDH1A1 (0.52) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28664287 | 0.83 | CACNA1H (0.39) | MEN1KMT2A | |
| SCHEMBL28658947 | 0.83 | KCNH2 (0.37) | MEN1KMT2A | |
| SCHEMBL28676235 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28655487 | 0.82 | SMYD3 (0.37) | MEN1KMT2A | |
| SCHEMBL28658945 | 0.82 | KCNH2 (0.36) | MEN1KMT2A | |
| SCHEMBL28670645 | 0.82 | MEN1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |