Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666537 | 0.79 | KMT2A (0.54) | KMT2AMEN1NPSR1ATMTDP1 | |
| SCHEMBL12914594 | 0.76 | NPSR1 (0.61) | KMT2AMEN1NPSR1ATMTDP1 | |
| SCHEMBL28665242 | 0.75 | KMT2A (0.47) | KMT2AMEN1NPSR1SMN1; SMN2ATM | |
| SCHEMBL30284171 | 0.75 | KMT2A (0.46) | KMT2AMEN1NPSR1SMN1; SMN2ATM | |
| SCHEMBL6671456 | 0.73 | SMN1; SMN2 (0.57) | KMT2ASMN1; SMN2L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL7350057 | 0.73 | ALDH1A1 (0.56) | KMT2AMEN1NPSR1SMN1; SMN2TDP1 | |
| SCHEMBL264029 | 0.72 | NPSR1 (0.56) | KMT2AMEN1NPSR1SMN1; SMN2ATM | |
| SCHEMBL6889531 | 0.72 | NPSR1 (0.56) | KMT2AMEN1NPSR1ATMTDP1 | |
| Biphenyl SCHEMBL23849576 | 0.72 | MAPT (0.46) | KMT2ACYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL21051097 | 0.72 | POLB (0.55) | KMT2ACYP2C9SMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651758-B | Synthetic method of benzo-hydrogenated imidazolone framework | 南通大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-113651758-A | Synthetic method of benzo-hydrogenated imidazolone framework | 南通大学 | 2021-11-16 | — | — | CN | disclosed |