Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminocaproic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 0.94 |
| ▸ | LMNA | P02545 | 4/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.94 |
| ▸ | THRB | P10828 | 2/20 | 0.94 |
| ▸ | MEN1 | O00255 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.94 |
| ▸ | RECQL | P46063 | 1/20 | 0.94 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.94 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.89 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.89 |
| ▸ | BLM | P54132 | 2/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.84 |
| ▸ | TSHR | P16473 | 6/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.74 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.74 |
| ▸ | GABRP | O00591 | 1/20 | 0.74 |
| ▸ | GABRD | O14764 | 1/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 12-Aminododecanoic Acid SCHEMBL8973700 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Octanedioate SCHEMBL261455 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| SCHEMBL2231728 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Adipic Acid SCHEMBL10591067 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Sebacic Acid SCHEMBL9501168 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Sebacic Acid SCHEMBL260910 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| 12-Aminododecanoic Acid SCHEMBL20767098 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Aminocaproic Acid SCHEMBL21141584 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Pimelic Acid SCHEMBL21465298 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 | |
| Adipic Acid SCHEMBL931429 | 0.97 | LMNA (1.00) | LMNAKMT2AALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118236978-A | Application of nickel-based metal organic framework Ni-MOFs material | 华南理工大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-113694969-B | Catalyst system and method for catalytically synthesizing 1, 6-hexamethylene diamine by using same | 河南平煤神马尼龙工程技术有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113694969-A | Catalyst system and method for catalytically synthesizing 1, 6-hexamethylene diamine by using same | 河南平煤神马尼龙工程技术有限公司 | 2021-11-26 | — | — | CN | disclosed |