SCHEMBL28660587

SCHEMBL28660587

CCOP(=O)(Nc1ccc(OC)cc1)OCC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.65
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
GAA P10253 4/20 0.49
LMNA P02545 2/20 0.49
HPGD P15428 2/20 0.49
MAPT P10636 5/20 0.47
KDM4E B2RXH2 5/20 0.47
NPC1 O15118 4/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP1A2 P05177 1/20 0.47
RAB9A P51151 3/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28659377 0.82 HTT (0.61) NPSR1PKMHTTSMN1; SMN2GAA
SCHEMBL10192180 0.81 NPSR1 (0.69) NPSR1HTTSMN1; SMN2GAALMNA
SCHEMBL28662107 0.80 LMNA (0.68) NPSR1PKMSMN1; SMN2GAALMNA
SCHEMBL14467691 0.79 NPSR1 (0.67) NPSR1PKMHTTSMN1; SMN2LMNA
SCHEMBL914682 0.79 NPSR1 (0.67) NPSR1HTTSMN1; SMN2GAALMNA
SCHEMBL1893010 0.79 NPSR1 (1.00) NPSR1HTTLMNAHPGDKDM4E
Ammonia Solution, Strong SCHEMBL9173134 0.77 NPSR1 (0.96) NPSR1HTTLMNAHPGDKDM4E
SCHEMBL10885930 0.76 NPSR1 (0.86) NPSR1HTTGAALMNAHPGD
SCHEMBL28665425 0.76 HTT (0.50) NPSR1PKMHTTSMN1; SMN2GAA
SCHEMBL28677973 0.76 HTT (0.50) NPSR1PKMHTTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801254-B Polypropylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2023-04-07 CN claimed
CN-113801254-A Polypropylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2021-12-17 CN claimed
CN-113801254-B Polypropylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2023-04-07 CN disclosed
CN-113801254-A Polypropylene catalyst and preparation method thereof 中国石油天然气股份有限公司 2021-12-17 CN disclosed