Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504008 | 0.82 | DDB1 (0.59) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28404362 | 0.82 | DDB1 (0.50) | DDB1CRBNALDH1A1 | |
| SCHEMBL14124937 | 0.79 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4962412 | 0.79 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3616336 | 0.79 | DDB1 (0.52) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL7383260 | 0.78 | DDB1 (0.55) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL31268167 | 0.77 | DDB1 (0.50) | DDB1CRBNALDH1A1NPC1RAB9A | |
| SCHEMBL1966881 | 0.76 | KMT2A (0.52) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL13311996 | 0.76 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6291490 | 0.75 | MAPT (0.35) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677666-A | Substituted bicyclic compounds as farnesoid X receptor modulators | 百时美施贵宝公司 | 2021-11-19 | — | — | CN | disclosed |