Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504008 | 0.86 | DDB1 (0.59) | DDB1CRBNALDH1A1 | |
| SCHEMBL31268160 | 0.85 | ALDH1A1 (0.50) | DDB1CRBNALDH1A1TSHRHTR2C | |
| SCHEMBL24969422 | 0.84 | ALDH1A1 (0.46) | DDB1CRBNALDH1A1TSHRHTR2C | |
| SCHEMBL4962412 | 0.83 | DDB1 (0.56) | DDB1CRBNALDH1A1 | |
| SCHEMBL14124937 | 0.83 | DDB1 (0.56) | DDB1CRBNALDH1A1 | |
| SCHEMBL28660703 | 0.82 | DDB1 (0.47) | DDB1CRBNALDH1A1 | |
| SCHEMBL7383260 | 0.81 | DDB1 (0.55) | DDB1CRBNALDH1A1 | |
| SCHEMBL13480664 | 0.81 | DDB1 (0.43) | DDB1CRBNALDH1A1TSHRHTR2C | |
| SCHEMBL25589991 | 0.79 | DDB1 (0.44) | DDB1CRBNALDH1A1TSHRHTR2C | |
| SCHEMBL1966881 | 0.79 | KMT2A (0.52) | DDB1CRBNALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196804-A | TGF- β R1 inhibitor and application thereof | 南京圣和药业股份有限公司 | 2020-05-26 | — | — | CN | disclosed |