SCHEMBL28660723

SCHEMBL28660723

CCCC[C@H](NCCNC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
GAA P10253 1/20 0.59
KMT2A Q03164 1/20 0.59
CTSK P43235 13/20 0.54
CTSS P25774 3/20 0.54
TDP1 Q9NUW8 1/20 0.46
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
NOD1 Q9Y239 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4317103 1.00 MEN1 (0.59) MEN1GAAKMT2ACTSKCTSS
SCHEMBL31325605 0.90 MEN1 (0.65) MEN1GAAKMT2ACTSKCTSS
SCHEMBL22433824 0.87 CTSK (0.50) MEN1GAAKMT2ACTSKCTSS
SCHEMBL21312432 0.84 MEN1 (0.57) MEN1GAAKMT2ACTSKCTSS
SCHEMBL26789194 0.84 MEN1 (0.61) MEN1GAAKMT2ACTSKCTSS
SCHEMBL25353243 0.84 MEN1 (0.69) MEN1GAAKMT2ACTSKCTSS
SCHEMBL31040386 0.84 MEN1 (0.65) MEN1GAAKMT2ACTSKCTSS
SCHEMBL25353238 0.84 MEN1 (0.69) MEN1GAAKMT2ACTSKCTSS
SCHEMBL2635341 0.82 MEN1 (0.59) MEN1GAAKMT2ACTSKCTSS
SCHEMBL2635343 0.82 MEN1 (0.59) MEN1GAAKMT2ACTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710687-A Cyclopeptide antibiotics 豪夫迈·罗氏有限公司 2021-11-26 CN disclosed