Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19065779 | 0.89 | MAPT (0.79) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL8834146 | 0.88 | KDM4E (0.50) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL7331180 | 0.83 | GAA (0.63) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL7034926 | 0.82 | MAPT (0.74) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL15528435 | 0.81 | TSHR (0.69) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL63699 | 0.81 | TSHR (0.61) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL17145917 | 0.81 | MAPT (0.67) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL8128228 | 0.81 | KDM4E (0.68) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL30294456 | 0.81 | MAPT (0.67) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL13224505 | 0.80 | MAPT (0.89) | MAPTALOX15KDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113768936-B | Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection | 南华大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-113768936-A | Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection | 南华大学 | 2021-12-10 | — | — | CN | disclosed |