Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CFTR | P13569 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTPRF | P10586 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28953721 | 0.98 | TSHR (0.59) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Benzene SCHEMBL28449714 | 0.98 | TSHR (0.59) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Fluoride SCHEMBL28310481 | 0.98 | TSHR (0.59) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| SCHEMBL29058049 | 0.89 | TSHR (0.50) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| SCHEMBL8589676 | 0.89 | CA1 (0.51) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| SCHEMBL28841525 | 0.85 | SLC6A3 (0.51) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| SCHEMBL15528435 | 0.84 | TSHR (0.69) | TSHRLMNAHSD17B10ALDH1A1KDM4E | |
| Dimethyl Phthalate SCHEMBL790124 | 0.84 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL29500970 | 0.84 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR | |
| Dimethyl Phthalate SCHEMBL34630 | 0.84 | TSHR (0.74) | TSHRLMNAHSD17B10ALDH1A1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930688-A | Tetrazazole tridentate chiral N, N, P-ligand (Zhang Yufeng type chiral anion ligand) derived from cinchona alkaloid, and preparation method and application thereof | 南方科技大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119776812-A | Chemical nickel-palladium ion plating activating solution for copper pads of display panel and preparation method thereof | 湖北兴福电子材料股份有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-118459482-A | Selenium-containing spiro compound and preparation method and application thereof | 华南理工大学 | 2024-08-09 | — | — | CN | claimed |
| CN-113980117-B | Fenpyroximate antigen and preparation method and application thereof | 西南大学 | 2024-07-12 | — | — | CN | claimed |
| CN-117865925-A | 3, 4-benzocoumarin compound based on complex functional aromatic hydrocarbon and preparation method and application thereof | 上海瑞苷生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117820460-A | Methoxypiperidine ethyl antigen and preparation method and application thereof | 西南大学 | 2024-04-05 | — | — | CN | claimed |
| CN-117003639-A | Preparation method of methyl o-iodobenzoate | 宿迁盛基医药科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116789667-A | Planar triarylamine molecule and synthesis method thereof | 天津大学 | 2023-09-22 | — | — | CN | claimed |
| CN-115925683-A | Dendritic carbazole pyridine formaldehyde compound, preparation method and application | 郑州大学 | 2023-04-07 | — | — | CN | claimed |
| CN-112707906-B | Novel organic electroluminescent material based on benzopyrrole diketone and application thereof | 安徽秀朗新材料科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-102702097-A | Preparation method of montelukast sodium intermediate | UNIV ZHEJIANG | 2012-10-03 | — | — | CN | claimed |
| CN-102321199-A | Schiff base rare-earth catalyst, preparation method and application | BEIJING INST TECHNOLOGY | 2012-01-18 | — | — | CN | claimed |
| CN-102260223-A | Serial-aristeromycin compounds containing 1,3-benzodiazole and synthesis method thereof | — | 2011-11-30 | — | — | CN | claimed |
| US-20100298571-A1 | ARYLAMINE SYNTHESIS METHOD | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2010-11-25 | — | — | US | claimed |
| WO-2010064109-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF MONTELUKAST SODIUM AND ITS INTERMEDIATES | MAYUKA LABS PRIVATE LIMITED (IN) | 2010-06-10 | — | — | WO | claimed |
| EP-1399156-B1 | ALKYLIDENE PIRAZOLIDINEDIONE DERIVATIVES AND THEIR USE FOR TREATING DIABETES AND OBESITY | APPLIED RESEARCH SYSTEMS (AN) | 2006-11-22 | — | — | EP | claimed |
| WO-2006021974-A1 | A PROCESS FOR SYNTHESIZING DIOL (VIII)-AN INTERMEDIATE OF MONTELUKAST SODIUM | MOREPEN LABORATORIES LIMITED (IN) | 2006-03-02 | — | — | WO | claimed |
| US-20040220188-A1 | Alkylidene pyrazolidinedione derivatives | LABORATOIRES SERONO SA (CH) | 2004-11-04 | — | — | US | claimed |
| EP-1399156-A2 | ALKYLIDENE PIRAZOLIDINEDIONE DERIVATIVES AND THEIR USE FOR TREATING DIABETES AND OBESITY | Applied Research Systems ARS Holding N.V. (AN) | 2004-03-24 | — | — | EP | claimed |
| WO-2002102359-A2 | ALKYLIDENE PYRAZOLIDINEDIONE DERIVATIVES AND USE FOR TREATING DIABETES AND OBESITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-12-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220188-A1 | Alkylidene pyrazolidinedione derivatives | G6PC1, PPM1D, PTPRS | TSHR 1160/4885LMNA 4876/4885HSD17B10 247/4885 |
| US-20100298571-A1 | ARYLAMINE SYNTHESIS METHOD | NAT1, ASNS, AOC2 | TSHR 1305/4885LMNA 2818/4885HSD17B10 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.