Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293397 | 1.00 | LMNA (0.58) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL236696 | 1.00 | LMNA (0.58) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL18155124 | 0.98 | LMNA (0.56) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL27544055 | 0.94 | LMNA (0.53) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Butanedione SCHEMBL27698634 | 0.93 | LMNA (0.56) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL26008133 | 0.93 | LMNA (0.51) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL236697 | 0.91 | LMNA (0.66) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL27946735 | 0.91 | LMNA (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL270754 | 0.88 | LMNA (0.69) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL27457920 | 0.88 | KDM4E (0.64) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825485-A | Improved fast breaking water-in-oil emulsion | 拜尔斯道夫股份有限公司 | 2021-12-21 | — | — | CN | claimed |