Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574475 | 0.84 | HRH3 (0.43) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL29285120 | 0.84 | CHRM3 (0.48) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL27945136 | 0.82 | CYP2D6 (0.54) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL28552734 | 0.82 | CHRM3 (0.39) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| Hydrochloric Acid SCHEMBL27926019 | 0.81 | MEN1 (0.55) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL28886385 | 0.81 | CHRM3 (0.41) | CHRM3 | |
| SCHEMBL28999420 | 0.79 | SMN1; SMN2 (0.43) | TP53CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL27762899 | 0.79 | CHRM3 (0.49) | CHRM3BCHE | |
| SCHEMBL28662442 | 0.78 | CHRM3 (0.44) | CHRM3 | |
| SCHEMBL28681273 | 0.78 | CHRM3 (0.52) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784969-A | PLK1 Selective degradation inducing Compounds | 厄普特拉公司 | 2021-12-10 | — | — | CN | disclosed |