Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886385 | 0.89 | CHRM3 (0.41) | CHRM3 | |
| SCHEMBL28662442 | 0.86 | CHRM3 (0.44) | CHRM3 | |
| SCHEMBL29285120 | 0.85 | CHRM3 (0.48) | CHRM3SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL28667844 | 0.84 | KDM4E (0.37) | CHRM3SMN1; SMN2CYP2D6MEN1ALDH1A1 | |
| SCHEMBL28552734 | 0.84 | CHRM3 (0.39) | CHRM3SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL28660967 | 0.84 | TP53 (0.54) | CHRM3SMN1; SMN2TP53CYP1A2CYP3A4 | |
| SCHEMBL28681265 | 0.82 | CHRM3 (0.38) | HRH3CHRM3MEN1ALDH1A1KMT2A | |
| SCHEMBL27762899 | 0.81 | CHRM3 (0.49) | CHRM3 | |
| SCHEMBL28999420 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2SLC18A3TP53CYP1A2CYP3A4 | |
| SCHEMBL28681273 | 0.80 | CHRM3 (0.52) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915903-A | Compounds for the treatment of neurodegenerative, degenerative and metabolic disorders and uses thereof | 佛罗里达大学研究基金会公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-110950843-B | Substituted benzamide derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-110963999-B | 2, 3-dihydrobenzofuran amide derivative and application thereof | 广东东阳光药业有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-110963999-A | 2, 3-dihydrobenzofuran amide derivative and application thereof | 广东东阳光药业有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-110950843-A | Substituted benzamide derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-03 | — | — | CN | disclosed |
| WO-2008071964-A1 | NAPHTHYRIDINE BACTERICIDES | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | WO | disclosed |