Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246418 | 0.89 | CYP2C9 (0.50) | CYP2C9PTGDR2PTGER2PTGDR | |
| SCHEMBL28665593 | 0.88 | CYP2C9 (0.51) | CYP2C9PTGDR2PTGER2PTGDRALDH1A1 | |
| SCHEMBL28675157 | 0.86 | PTGDR2 (0.48) | CYP2C9PTGDR2PTGER2PTGDR | |
| SCHEMBL28680236 | 0.84 | PARP1 (0.50) | CYP2C9PTGDR2PTGER2PTGDR | |
| SCHEMBL28668268 | 0.83 | PTGDR2 (0.56) | CYP2C9PTGDR2 | |
| SCHEMBL29246417 | 0.83 | PTGDR2 (0.54) | CYP2C9PTGDR2 | |
| SCHEMBL28675151 | 0.83 | — | — | |
| SCHEMBL28688188 | 0.82 | CYP2C9 (0.51) | CYP2C9PTGDR2 | |
| SCHEMBL28689649 | 0.82 | CYP2C9 (0.65) | CYP2C9PTGDR2PTGER2PTGDR | |
| SCHEMBL28930615 | 0.81 | PTGDR2 (0.54) | CYP2C9PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845522-A | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2021-12-28 | — | — | CN | claimed |
| CN-113845522-B | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2024-05-14 | — | — | CN | disclosed |
| CN-113845522-A | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2021-12-28 | — | — | CN | disclosed |