Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246418 | 0.91 | CYP2C9 (0.50) | PARP1PARP2PTGDR2PTGER2PTGDR | |
| SCHEMBL28930608 | 0.88 | PTGDR2 (0.49) | PTGDR2PTGER2PTGDRCYP2C9 | |
| SCHEMBL29246417 | 0.87 | PTGDR2 (0.54) | PTGDR2CYP2C9 | |
| SCHEMBL28688193 | 0.86 | PTGDR2 (0.52) | PTGDR2CYP2C9 | |
| SCHEMBL28688188 | 0.86 | CYP2C9 (0.51) | PTGDR2CYP2C9 | |
| SCHEMBL28661635 | 0.84 | CYP2C9 (0.51) | PTGDR2PTGER2PTGDRCYP2C9 | |
| SCHEMBL28675157 | 0.82 | PTGDR2 (0.48) | PTGDR2PTGER2PTGDRCYP2C9 | |
| SCHEMBL28930600 | 0.81 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL28668268 | 0.79 | PTGDR2 (0.56) | PTGDR2CYP2C9 | |
| SCHEMBL28689653 | 0.79 | PTGDR2 (0.52) | PTGDR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845522-A | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2021-12-28 | — | — | CN | claimed |
| CN-113845522-B | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2024-05-14 | — | — | CN | disclosed |
| CN-113845522-A | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2021-12-28 | — | — | CN | disclosed |