Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 16/20 | 0.68 |
| ▸ | MERTK | Q12866 | 5/20 | 0.68 |
| ▸ | AXL | P30530 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28667889 | 0.94 | MERTK (0.71) | TYRO3MERTKAXL | |
| SCHEMBL28671429 | 0.82 | TYRO3 (0.68) | TYRO3MERTKAXL | |
| SCHEMBL29625541 | 0.81 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL19377547 | 0.81 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL19377567 | 0.79 | MERTK (1.00) | TYRO3MERTKAXL | |
| SCHEMBL29626172 | 0.78 | TYRO3 (0.71) | TYRO3MERTKAXL | |
| SCHEMBL29626136 | 0.78 | MERTK (0.68) | TYRO3MERTKAXL | |
| SCHEMBL28689844 | 0.77 | TYRO3 (0.69) | TYRO3MERTKAXL | |
| SCHEMBL27088332 | 0.75 | TYRO3 (0.70) | TYRO3MERTKAXL | |
| SCHEMBL29626144 | 0.74 | TYRO3 (0.66) | TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456175-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114456176-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114456175-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-109348715-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2021-12-31 | — | — | CN | disclosed |