Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.69 |
| ▸ | CASP1 | P29466 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | CASP7 | P55210 | 2/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.66 |
| ▸ | TUBB | P07437 | 2/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628033 | 1.00 | MEN1 (0.69) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL4333738 | 0.91 | TUBB4A (0.69) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL30628022 | 0.89 | POLB (0.73) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL28927732 | 0.89 | MEN1 (0.70) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL28644827 | 0.89 | POLB (0.73) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL30628023 | 0.89 | MEN1 (0.70) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL4330162 | 0.88 | MEN1 (0.76) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL30628028 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL28650070 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL4331607 | 0.88 | MEN1 (0.79) | MEN1KMT2AMAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620919-B | Mechanical ball milling assisted synthesis method of 2-amino-3-cyano-4H-pyran compound | 浙江工业大学 | 2023-12-12 | — | — | CN | disclosed |
| CN-113620919-A | Mechanical ball-milling auxiliary synthesis method of 2-amino-3-cyano-4H-pyran compounds | 浙江工业大学 | 2021-11-09 | — | — | CN | disclosed |