Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753206 | 0.87 | RECQL (0.50) | LMNARORBRORCKMT2ARECQL | |
| SCHEMBL31565655 | 0.87 | RECQL (0.50) | LMNARORBRORCKMT2ARECQL | |
| SCHEMBL29577063 | 0.86 | NNMT (0.42) | NNMTNAPRTSIRT6HPGDPPARG | |
| SCHEMBL16333365 | 0.86 | NNMT (0.42) | NNMTNAPRTSIRT6HPGDPPARG | |
| SCHEMBL29446081 | 0.84 | SMN1; SMN2 (0.47) | NNMTNAPRTSIRT6SMN1; SMN2LMNA | |
| SCHEMBL625580 | 0.84 | SMN1; SMN2 (0.47) | NNMTNAPRTSIRT6SMN1; SMN2LMNA | |
| SCHEMBL13304188 | 0.83 | NNMT (0.43) | NNMTNAPRTSIRT6HPGDSMN1; SMN2 | |
| SCHEMBL29562604 | 0.83 | NNMT (0.43) | NNMTNAPRTSIRT6HPGDSMN1; SMN2 | |
| SCHEMBL29799541 | 0.83 | NNMT (0.61) | NNMTSIRT6LMNAKMT2A | |
| SCHEMBL27417396 | 0.83 | NNMT (0.40) | NNMTNAPRTSIRT6HPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620949-A | Synthesis method of antitumor compound and intermediate thereof | 南京药捷安康生物科技有限公司 | 2021-11-09 | — | — | CN | disclosed |