Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987230 | 0.90 | EPHX2 (0.70) | MEN1KMT2ACYP1A2CYP2C19RAB9A | |
| SCHEMBL28643603 | 0.89 | PPARG (0.67) | RAB9ASMN1; SMN2EPHX2NR1H4PPARG | |
| SCHEMBL11473837 | 0.88 | NPC1 (0.66) | MEN1KMT2ACYP1A2CYP2C19RAB9A | |
| SCHEMBL11471260 | 0.88 | NPC1 (0.66) | MEN1KMT2ACYP1A2CYP2C19RAB9A | |
| SCHEMBL8987867 | 0.83 | MEN1 (0.78) | MEN1KMT2ACYP1A2CYP2C19RAB9A | |
| SCHEMBL2418582 | 0.83 | LTB4R (0.66) | SMN1; SMN2POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL28658499 | 0.83 | NPC1 (0.64) | MEN1KMT2ARAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL11204036 | 0.82 | MAPT (0.69) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10276969 | 0.82 | MAPT (0.69) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL951697 | 0.82 | MAPT (0.69) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |