Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 4/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663018 | 1.00 | PSMB8 (0.34) | PSMB8SCN10ADHODHULK1CYP2D6 | |
| SCHEMBL18849672 | 1.00 | PSMB8 (0.34) | PSMB8SCN10ADHODHULK1CYP2D6 | |
| SCHEMBL18849829 | 0.93 | PSMB8 (0.34) | PSMB8SCN10ADHODHULK1CYP2D6 | |
| SCHEMBL28641205 | 0.93 | PSMB8 (0.34) | PSMB8SCN10ADHODHULK1CYP2D6 | |
| SCHEMBL18849645 | 0.93 | PSMB8 (0.34) | PSMB8SCN10ADHODHULK1CYP2D6 | |
| SCHEMBL28641202 | 0.93 | PSMB8 (0.34) | PSMB8SCN10ADHODHULK1CYP2D6 | |
| SCHEMBL18849636 | 0.93 | MAOA (0.35) | CYP2D6CYP2C9MAOAMAOBCTSC | |
| SCHEMBL18849736 | 0.89 | PSMB8 (0.44) | PSMB8SCN10ADHODHULK1IKBKB | |
| SCHEMBL28638185 | 0.89 | PSMB8 (0.44) | PSMB8SCN10ADHODHULK1IKBKB | |
| SCHEMBL18849853 | 0.85 | PSMB8 (0.35) | PSMB8SCN10ADHODHULK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349945-B | HCV inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-10-29 | — | — | CN | disclosed |