SCHEMBL2866342

SCHEMBL2866342

CCc1c(O)cc(-c2ccccc2)c(O)c1CC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.54
PDE4B Q07343 3/20 0.47
POLB P06746 2/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PDE4A P27815 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
ALOX5 P09917 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ESR2 Q92731 3/20 0.41
ESR1 P03372 2/20 0.41
PTPN1 P18031 3/20 0.40
USP7 Q93009 2/20 0.40
PTPN2 P17706 1/20 0.40
PTPN6 P29350 1/20 0.40
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11022297 0.84 PTPN1 (0.42) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL1978315 0.83 ESR2 (0.50) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL2879317 0.82 BACE1 (0.50) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL30516125 0.80 BACE1 (0.52) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL2870897 0.80 HDAC4 (0.44) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL27864327 0.80 BACE1 (0.52) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL2863890 0.80 HPGD (0.47) BACE1PDE4BPDE4APDE4CPDE4D
SCHEMBL30717194 0.79 BACE1 (0.50) BACE1PDE4BPOLBRECQLSMN1; SMN2
Potassium SCHEMBL30717195 0.79 BACE1 (0.50) BACE1PDE4BPOLBRECQLSMN1; SMN2
SCHEMBL2148888 0.77 BACE1 (0.48) BACE1PDE4BPOLBRECQLSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed