SCHEMBL1978315

SCHEMBL1978315

CCc1c(O)ccc(-c2ccccc2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.50
BACE1 P56817 2/20 0.50
ESR1 P03372 2/20 0.50
ALOX5 P09917 2/20 0.48
PDE4B Q07343 3/20 0.45
PDE4A P27815 2/20 0.45
PDE4C Q08493 2/20 0.45
PDE4D Q08499 2/20 0.45
USP7 Q93009 2/20 0.44
POLB P06746 1/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
BCL2L1 Q07817 1/20 0.43
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30234292 0.87 ESR2 (0.53) ESR2BACE1ESR1ALOX5PDE4B
SCHEMBL2201812 0.87 ESR2 (0.53) ESR2BACE1ESR1ALOX5PDE4B
SCHEMBL2870986 0.85 BACE1 (0.42) ESR2BACE1ESR1ALOX5PDE4B
SCHEMBL2866342 0.83 BACE1 (0.54) ESR2BACE1ESR1ALOX5PDE4B
SCHEMBL2865287 0.82 GCGR (0.44) ESR2BACE1ESR1ALOX5ALDH1A1
Formaldehyde SCHEMBL29141443 0.82 ESR2 (0.49) ESR2BACE1ESR1ALOX5PDE4B
SCHEMBL2864086 0.81 GCGR (0.50) ALDH1A1HPGDHSD17B10KDM4EGCGR
SCHEMBL8926006 0.80 ESR1 (0.57) ESR2BACE1ESR1ALOX5PDE4B
Propane SCHEMBL27443402 0.80 BACE1 (0.48) ESR2BACE1ESR1ALOX5PDE4B
SCHEMBL2855337 0.80 GCGR (0.49) ALOX5ALDH1A1HPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326892-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS Institute of Life Science (FR) 2024-02-28 EP claimed
WO-2022223928-A1 METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA NAOS INSTITUTE OF LIFE SCIENCE (FR) 2022-10-27 WO claimed
US-20210030141-A1 MASK, DEVICE, AND METHOD FOR WHITENING SKIN GOO BONCHEOL (KR) 2021-02-04 US claimed
EP-3528775-A1 PROCESS FOR TREATING HAIR Kao Germany GmbH (DE) 2019-08-28 EP claimed
WO-2018110273-A1 A COMPOSITION INCLUDING SPARINGLY WATER-SOLUBLE ACTIVE PHENOLIC COMPOUND AND VINYLPYRROLIDONE COPOLYMER L'OREAL (FR) 2018-06-21 WO claimed
WO-2017167596-A1 PROCESS FOR TREATING HAIR KAO GERMANY GMBH (DE) 2017-10-05 WO claimed
EP-3225229-A1 PROCESS FOR TREATING HAIR Kao Germany GmbH (DE) 2017-10-04 EP claimed
CN-121731148-A Mesoporous silica nanoparticle whitening essence loaded with whitening active ingredients 中航科学研究院(广东)有限公司 2026-03-27 CN disclosed
US-20260047990-A1 Compositions and Methods for Treating Skin Discoloration RACQUEL FRISELLA LLC (US) 2026-02-19 US disclosed
EP-4554549-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT OR CELLULOSE COMPOUND L'OREAL (FR) 2025-05-21 EP disclosed
WO-2025098825-A1 A PERSONAL CARE COMPOSITION AND A METHOD OF TREATING SKIN UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
WO-2025098792-A1 USE OF A SKIN BENEFIT AGENT IN RESTORING SKIN'S BARRIER FUNCTION UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
WO-2025098793-A1 USE OF A SKIN BENEFIT AGENT IN BOOSTING SKIN'S NIGHT REPAIR FUNCTION UNILEVER IP HOLDINGS B.V. (NL) 2025-05-15 WO disclosed
US-20110142897-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT L'OREAL (FR) 2011-06-16 US disclosed
EP-2254546-A2 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN ELC Management LLC (US) 2010-12-01 EP disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
WO-2009105294-A2 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN ELC MANAGEMENT LLC (US) 2009-08-27 WO disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260047990-A1 Compositions and Methods for Treating Skin Discoloration TYR, TH, DYRK1A ESR2 2974/4885BACE1 4644/4885ESR1 2628/4885
US-20110142897-A1 PROCESS FOR TREATMENT OF KERATINOUS MATERIALS AND KIT FOR FORMULATION OF A COSMETIC PRODUCT CUTA, KRT18, KIT ESR2 4287/4885BACE1 2720/4885ESR1 4521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.